Genevieve M Leyden

Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics

Xiaodun Li, Hayley E. Francies, Maria Secrier et al. · Nature Communications · 2018 · 327 citations · Full text

Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation

Tom G. Richardson, Genevieve M Leyden, Qin Wang et al. · PLoS Biology · 2022 · 290 citations · Full text

Drug Target, Large-scale Molecular Profiling, Metabolomic Profiling +21

Harnessing tissue-specific genetic variation to dissect putative causal pathways between body mass index and cardiometabolic phenotypes

Genevieve M Leyden, Chin Yang Shapland, George Davey Smith et al. · The American Journal of Human Genetics · 2022 · 35 citations · Full text

Obesity, Metabolic Syndrome, Cardiomyopathy +13

A lifecourse mendelian randomization study highlights the long-term influence of childhood body size on later life heart structure

Katie O’Nunain, Chloe Park, Helena Urquijo et al. · PLoS Biology · 2022 · 28 citations · Full text

Multi-omics analyses of cognitive traits and psychiatric disorders highlight brain-dependent mechanisms

Roxanna Korologou‐Linden, Genevieve M Leyden, Caroline L. Relton et al. · Human Molecular Genetics · 2021 · 23 citations · Full text

Neuropsychology, Neurogenomics, Brain Function +33