Siân E. Piret

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

Jenny C. Taylor, Hilary C. Martin, Stefano Lise et al. · Nature Genetics · 2015 · 378 citations · Full text

Sequencing, Psychiatry, Clinical Genome +8

Loss of proximal tubular transcription factor Krüppel-like factor 15 exacerbates kidney injury through loss of fatty acid oxidation

Siân E. Piret, Ahmed A. Attallah, Xiangchen Gu et al. · Kidney International · 2021 · 83 citations · Full text

Inflammation, Renal Function, Biochemistry +13

Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients

Caroline M. Gorvin, Martijn J. Wilmer, Siân E. Piret et al. · Proceedings of the National Academy of Sciences · 2013 · 82 citations · Full text

Renal Pathology, Pathology, Cytoskeleton +20

Gα11 mutation in mice causes hypocalcemia rectifiable by calcilytic therapy

Caroline M. Gorvin, Fadil Hannan, Sarah Howles et al. · JCI Insight · 2017 · 66 citations · Full text

Krüppel-like factor 6–mediated loss of BCAA catabolism contributes to kidney injury in mice and humans

Siân E. Piret, Yiqing Guo, Ahmed A. Attallah et al. · Proceedings of the National Academy of Sciences · 2021 · 65 citations · Full text