Madeleine Héroux

Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs

Charlotte Avet, Arturo Mancini, Billy Breton et al. · eLife · 2022 · 240 citations · Full text

Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization

Ajamete Kaykas, Julia Yang-Snyder, Madeleine Héroux et al. · Nature Cell Biology · 2003 · 172 citations

Pathogenesis, Endocytic Pathway, Molecular Biology +5

Functional Calcitonin Gene-related Peptide Receptors Are Formed by the Asymmetric Assembly of a Calcitonin Receptor-like Receptor Homo-oligomer and a Monomer of Receptor Activity-modifying Protein-1

Madeleine Héroux, Mireille Hogue, Sébastien Lemieux et al. · Journal of Biological Chemistry · 2007 · 79 citations · Full text

Molecular Biology, Receptor Activity-modifying Protein-1, Bimolecular Fluorescence Complementation +17

Comparing Label-Free Biosensors for Pharmacological Screening With Cell-Based Functional Assays

Matthew F. Peters, François Vaillancourt, Madeleine Héroux et al. · Assay and Drug Development Technologies · 2010 · 69 citations

Engineering, Peptide Science, Impedance-based Biosensor +19

BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G _q activation at early endosomes

Shane C. Wright, Viktoriya Lukasheva, Christian Le Gouill et al. · Proceedings of the National Academy of Sciences · 2021 · 63 citations · Full text