John A. Chaddock

Inhibition of Release of Neurotransmitters from Rat Dorsal Root Ganglia by a Novel Conjugate of a Clostridium botulinumToxin A Endopeptidase Fragment and Erythrina cristagalliLectin

Michael Duggan, Conrad P. Quinn, John A. Chaddock et al. · Journal of Biological Chemistry · 2002 · 122 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

The structure and function of ribosome-inactivating proteins

Martin R. Hartley, John A. Chaddock, Maureen S. Bonness · Trends in Plant Science · 1996 · 71 citations

Life Sciences, Biochemistry, Molecular Biology +12

Retargeted clostridial endopeptidases: Inhibition of nociceptive neurotransmitter release in vitro, and antinociceptive activity in in vivo models of pain

John A. Chaddock, John R. Purkiss, Frances C.G. Alexander et al. · Movement Disorders · 2004 · 67 citations

Medicine, Neuroscience, Pharmacology +17

Expression and purification of catalytically active, non-toxic endopeptidase derivatives of Clostridium botulinum toxin type A

John A. Chaddock, Michael H. Herbert, Roger Ling et al. · Protein Expression and Purification · 2002 · 65 citations

Life Sciences, Biochemistry, Molecular Biology +9

Inhibition of Vesicular Secretion in Both Neuronal and Nonneuronal Cells by a Retargeted Endopeptidase Derivative of <i>Clostridium botulinum</i> Neurotoxin Type A

John A. Chaddock, John R. Purkiss, Lorna M. Friis et al. · Infection and Immunity · 2000 · 64 citations

Life Sciences, Biochemistry, Neurobiology +16