Mark Michael

(R)-8-(3-Amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a Novel Xanthine-Based Dipeptidyl Peptidase 4 Inhibitor, Has a Superior Potency and Longer Duration of Action Compared with Other Dipeptidyl Peptidase-4 Inhibitors

Leo Thomas, Matthias Eckhardt, Elke Langkopf et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 280 citations

Medicine, Medicinal Chemistry, Pharmacology +8

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

Natalie R. van Zuydam, Emma Ahlqvist, Niina Sandholm et al. · Diabetes · 2018 · 197 citations · Full text

Medicine, Endocrinology, Molecular Genetics +17

Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury

Pinelopi P. Kapitsinou, Hideto Sano, Mark Michael et al. · Journal of Clinical Investigation · 2014 · 195 citations · Full text

Medicine, Molecular Biology, Pathobiology +17

The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice

Pinelopi P. Kapitsinou, Ganeshkumar Rajendran, Lindsay Astleford et al. · Molecular and Cellular Biology · 2016 · 134 citations · Full text

Life Sciences, Genetics, Physiology +17

Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury

Pinelopi P. Kapitsinou, Jonathan T. Jaffe, Mark Michael et al. · American Journal of Physiology-Renal Physiology · 2012 · 116 citations · Full text

Medicine, Nephrology, Pathobiology +17