Subra Kugathasan

The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

Dirk Gevers, Subra Kugathasan, Lee A. Denson et al. · Cell Host & Microbe · 2014 · 3.3K citations · Full text

Life Sciences, Immunology, Microbiology +13

A genomic mutational constraint map using variation in 76,156 human genomes

Siwei Chen, Laurent C. Francioli, Julia K. Goodrich et al. · Nature · 2023 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

A structural variation reference for medical and population genetics

Ryan L. Collins, Harrison Brand, Konrad J. Karczewski et al. · Nature · 2020 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy

J.P. Martin, Christie Chang, Gilles Boschetti et al. · Cell · 2019 · 898 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Induction and Maintenance Infliximab Therapy for the Treatment of Moderate-to-Severe Crohn’s Disease in Children

Jeffrey S. Hyams, Wallace Crandall, Subra Kugathasan et al. · Gastroenterology · 2006 · 870 citations · Full text

Pharmacy, Immunology, Pharmacotherapy +12