Silva Hečimović

A presenilin dimer at the core of the γ-secretase enzyme: Insights from parallel analysis of Notch 1 and APP proteolysis

Eric H. Schroeter, Ma. Xenia G. Ilagan, Anne L. Brunkan et al. · Proceedings of the National Academy of Sciences · 2003 · 198 citations · Full text

Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington’s disease gene carriers and healthy subjects

N. Klepac, Maja Relja, R. Klepac et al. · Journal of Neurology · 2007 · 170 citations

Redox Signaling, Neurodegenerative Diseases, Disease Gene Carriers +12

Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins

Stjepko Čermak, Marko Košiček, Aleksandra Mladenović et al. · PLoS ONE · 2016 · 152 citations · Full text

Free Cholesterol, Cell Death, Neurochemical Biomarkers +22

The Low Density Lipoprotein Receptor-related Protein 1B Retains β-Amyloid Precursor Protein at the Cell Surface and Reduces Amyloid-β Peptide Production

Judy Cam, Celina Zerbinatti, Jane M. Knisely et al. · Journal of Biological Chemistry · 2004 · 111 citations · Full text

Proteinlipid Interaction, Protein Function, Biochemistry +13

Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia

Alessio Colombo, Lina Dinkel, Stephan A. Müller et al. · Nature Communications · 2021 · 103 citations · Full text