Nicole C. Goodwin

The First Enantioselective Organocatalytic Mukaiyama−Michael Reaction:  A Direct Method for the Synthesis of Enantioenriched γ-Butenolide Architecture

Sean P. Brown, Nicole C. Goodwin, David W. C. MacMillan · Journal of the American Chemical Society · 2003 · 443 citations

LX4211, a Dual SGLT1/SGLT2 Inhibitor, Improved Glycemic Control in Patients With Type 2 Diabetes in a Randomized, Placebo-Controlled Trial

Brian Zambrowicz, J Freiman, Phil Brown et al. · Clinical Pharmacology & Therapeutics · 2012 · 235 citations · Full text

Novel <scp>l</scp>-Xylose Derivatives as Selective Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitors for the Treatment of Type 2 Diabetes

Nicole C. Goodwin, Ross Mabon, Bryce A. Harrison et al. · Journal of Medicinal Chemistry · 2009 · 76 citations · Full text

Medicinal Chemistry, Diabetes Management, Biochemistry +13

Site-Selective C–H Alkylation of Piperazine Substrates via Organic Photoredox Catalysis

Joshua B. McManus, Nicholas P. R. Onuska, Matthew S. Jeffreys et al. · Organic Letters · 2020 · 68 citations

Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation

Nicole C. Goodwin, Giovanni Cianchetta, Hugh A. Burgoon et al. · ACS Medicinal Chemistry Letters · 2014 · 66 citations · Full text

Drug Target, Molecular Biology, Lim Kinase 2 +23