Gino Salituro

Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

Bei Zhang, Gino Salituro, Deborah Szalkowski et al. · Science · 1999 · 453 citations

Insulin Receptor, Insulin Signaling, Cell Surface Receptor +16

Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity

Ellen L. Air, Mathias Z. Strowski, Stephen C. Benoit et al. · Nature Medicine · 2002 · 167 citations

Obesity, Metabolic Syndrome, Biochemistry +13

Omarigliptin (MK-3102): A Novel Long-Acting DPP-4 Inhibitor for Once-Weekly Treatment of Type 2 Diabetes

Tesfaye Biftu, Ranabir SinhaRoy, Ping Chen et al. · Journal of Medicinal Chemistry · 2014 · 167 citations · Full text

Medicinal Chemistry, Scientific Rationale, Available Dpp-4 Inhibitors +14

Selective Small-Molecule Agonists of G Protein–Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice

Carina P. Tan, Yue Feng, Yun-Ping Zhou et al. · Diabetes · 2008 · 164 citations · Full text

Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes

Margaret Wu, Sheo B. Singh, Jun Wang et al. · Proceedings of the National Academy of Sciences · 2011 · 145 citations

Fatty Acid Synthase, Insulin Signaling, Db/db Mice +16