Nathalie Erdeljac

Fluorinated Analogues of the Histone Deacetylase Inhibitor Vorinostat (Zolinza): Validation of a Chiral Hybrid Bioisostere, BITE

Nathalie Erdeljac, Kathrin Bussmann, Andrea Schöler et al. · ACS Medicinal Chemistry Letters · 2019 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Exploring physicochemical space <i>via</i> a bioisostere of the trifluoromethyl and ethyl groups (BITE): attenuating lipophilicity in fluorinated analogues of Gilenya® for multiple sclerosis

Nathalie Erdeljac, Gerald Kehr, Marie Ahlqvist et al. · Chemical Communications · 2018 · 41 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Stereocontrolled Synthesis of Tetrafluoropentanols: Multivicinal Fluorinated Alkane Units for Drug Discovery

Patrick Bentler, Nathalie Erdeljac, Kathrin Bussmann et al. · Organic Letters · 2019 · 31 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Validating the 1,2-Difluoro Motif As a Hybrid Bioisostere of CF₃ and Et Using Matrix Metalloproteinases As Structural Probes

Nathalie Erdeljac, Christian Thiehoff, Ravindra P. Jumde et al. · Journal of Medicinal Chemistry · 2020 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15