Leila R. Martins

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

Ana Silva, José Andrés Yunes, Bruno A. Cardoso et al. · Journal of Clinical Investigation · 2008 · 441 citations · Full text

Pten Activity, Signal Transduction, Cell Regulation +14

Low Doses of Ionizing Radiation Promote Tumor Growth and Metastasis by Enhancing Angiogenesis

Inês Sofia Vala, Leila R. Martins, Natsuko Imaizumi et al. · PLoS ONE · 2010 · 183 citations · Full text

Radiation Effect, Radiation Exposure, Zebrafish Fin Regeneration +21

IL-7 Contributes to the Progression of Human T-cell Acute Lymphoblastic Leukemias

Ana Silva, Angelo B. A. Laranjeira, Leila R. Martins et al. · Cancer Research · 2011 · 140 citations

Hematological Malignancy, Microenvironmental Factors, Autoimmune Disease +15

Adult B-cell acute lymphoblastic leukemia cells display decreased PTEN activity and constitutive hyperactivation of PI3K/Akt pathway despite high PTEN protein levels

Ana Margarida Gomes, Maria V. D. Soares, Patrick Rasmussen Ribeiro et al. · Haematologica · 2014 · 84 citations · Full text

Protein Kinase Ck2, Mixed-phenotype Acute Leukemia, Immunology +16

Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling

Francesca Buontempo, Ester Orsini, Leila R. Martins et al. · Leukemia · 2013 · 81 citations · Full text

Hematological Malignancy, Inhibitor Cx-4945, Receptor Tyrosine Kinase +10