Leonie M. Middelink

Early rheumatoid arthritis treated with tocilizumab, methotrexate, or their combination (U-Act-Early): a multicentre, randomised, double-blind, double-dummy, strategy trial

J. W. J. Bijlsma, Paco M J Welsing, Thasia Woodworth et al. · The Lancet · 2016 · 238 citations

Rheumatoid Disorder, Rheumatology, Autoimmune Disease +8

Harm, benefit and costs associated with low-dose glucocorticoids added to the treatment strategies for rheumatoid arthritis in elderly patients (GLORIA trial): study protocol for a randomised controlled trial

Linda Hartman, Linda A. Rasch, Thomas Klausch et al. · Trials · 2018 · 39 citations · Full text

Intravenous pegylated liposomal prednisolone outperforms intramuscular methylprednisolone in treating rheumatoid arthritis flares: A randomized controlled clinical trial

Josbert M. Metselaar, Leonie M. Middelink, Cornelis H. Wortel et al. · Journal of Controlled Release · 2021 · 30 citations

Inflammation, Rheumatology, Rheumatoid Disorder +11

A phase I/IIa safety and efficacy trial of intratympanic gamma-secretase inhibitor as a regenerative drug treatment for sensorineural hearing loss

Anne GM Schilder, Stephan Wolpert, Shakeel R. Saeed et al. · Nature Communications · 2024 · 24 citations · Full text