Shana Y. Trostel

EZH2 inhibition activates a dsRNA–STING–interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer

Katherine L. Morel, Anjali V. Sheahan, Deborah L. Burkhart et al. · Nature Cancer · 2021 · 241 citations · Full text

Medicine, Molecular Biology, Oncology +12

Microtubule-targeting agents augment the toxicity of DNA-damaging agents by disrupting intracellular trafficking of DNA repair proteins

Marianne S. Poruchynsky, Edina Komlódi-Pásztor, Shana Y. Trostel et al. · Proceedings of the National Academy of Sciences · 2015 · 182 citations · Full text

Life Sciences, Cancer Biology, Oncology +16

Depletion of Mutant p53 and Cytotoxicity of Histone Deacetylase Inhibitors

Mikhail V. Blagosklonny, Shana Y. Trostel, Ganesh Kayastha et al. · Cancer Research · 2005 · 84 citations · Full text

Medicine, Cancer Biology, Oncology +17

Low Abundance of Circulating Tumor DNA in Localized Prostate Cancer

S. Thomas Hennigan, Shana Y. Trostel, Nicholas T. Terrigino et al. · JCO Precision Oncology · 2019 · 80 citations · Full text

Medicine, Molecular Medicine, Oncology +17

Nascent Prostate Cancer Heterogeneity Drives Evolution and Resistance to Intense Hormonal Therapy

Scott Wilkinson, Huihui Ye, Fatima Karzai et al. · European Urology · 2021 · 74 citations · Full text

Medicine, Oncology, Urology +17