Jonathan Barlow

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner

Alex P. Seabright, Nicholas H. F. Fine, Jonathan Barlow et al. · The FASEB Journal · 2020 · 148 citations · Full text

Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells

Jonathan Barlow, Charles Affourtit · Biochemical Journal · 2013 · 50 citations · Full text

Mitochondrial Dysfunction, Mitochondrial Dysfunction Contributes, Mitochondrial Biology +19

Palmitate-induced impairment of glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets

Jonathan Barlow, Verena Hirschberg, Martin Jastroch et al. · Biochemical Journal · 2015 · 47 citations · Full text

Mitochondrial Dysfunction, Mitochondrial Biology, Insulin Signaling +20

Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment

Silvia Panetti, Nicola McJannett, Livingstone Fultang et al. · Blood Advances · 2022 · 39 citations · Full text

Amino Acids, Tumor Environment, T-regulatory Cell +17

Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity – Novel mechanistic insight from real-time analysis of oxidative phosphorylation

Jonathan Barlow, Thomas P. J. Solomon, Charles Affourtit · PLoS ONE · 2018 · 35 citations · Full text

Mitochondrial Dysfunction, Mitochondrial Biology, Redox Biology +20