Frédérique Pilon

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy

François Binet, Gaël Cagnone, Sergio Crespo‐Garcia et al. · Science · 2020 · 272 citations

Ocular Disease, Immunology, Retinal Therapies +18

Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition

Sergio Crespo‐Garcia, Pamela R. Tsuruda, Agnieszka Dejda et al. · Cell Metabolism · 2021 · 173 citations · Full text

Ocular Disease, Angiogenesis, Ophthalmology +10

Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation

Masayuki Hata, Elisabeth M. M. A. Andriessen, Maki Hata et al. · Science · 2023 · 155 citations

Innate Immune System, Immunology, Cell Death +22

Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome

Ariel M. Wilson, Zhuo Shao, Vanessa Grenier et al. · Science Immunology · 2018 · 57 citations

Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life

Masayuki Hata, Maki Hata, Elisabeth M. M. A. Andriessen et al. · Journal of Clinical Investigation · 2023 · 27 citations · Full text

Ocular Disease, Pathological Neovascularization, Innate Immune System +19