Ben Powney

Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability

Thomas Briston, Malcolm C. Roberts, Siân Lewis et al. · Scientific Reports · 2017 · 141 citations · Full text

Protean Agonism at the Dopamine D2 Receptor: (S)-3-(3-Hydroxyphenyl)-N-propylpiperidine Is an Agonist for Activation of Go1 but an Antagonist/Inverse Agonist for Gi1,Gi2, and Gi3

J. Robert Lane, Ben Powney, Alan Wise et al. · Molecular Pharmacology · 2007 · 67 citations

G Protein Coupling and Ligand Selectivity of the D2L and D3 Dopamine Receptors

J. Robert Lane, Ben Powney, Alan Wise et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 62 citations

Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria

Thomas Briston, Siân Lewis, Mumta Koglin et al. · Scientific Reports · 2016 · 30 citations · Full text

The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2

Pier Luca D’Alessandro, Corrado Corti, Adelheid Roth et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 23 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +6