Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages

Jennifer M. Rosenbluth, Ron C.J. Schackmann, G. Kenneth Gray, +11

Nature Communications

Mass cytometry of Hodgkin lymphoma reveals a CD4+ regulatory T-cell–rich and exhausted T-effector microenvironment

Fathima Zumla Cader, Ron C.J. Schackmann, Xihao Hu, +14

Blood

Rapid Sequential in Situ Multiplexing with DNA Exchange Imaging in Neuronal Cells and Tissues

Yu Wang, Johannes B. Woehrstein, Noah D. Donoghue, +14

Nano Letters

EngineeringMolecular BiologyUnlimited MultiplexingTissue ImagingComputational Imaging +21

A human breast atlas integrating single-cell proteomics and transcriptomics

G. Kenneth Gray, Carman Man-Chung Li, Jennifer M. Rosenbluth, +16

Developmental Cell

Human BreastFunctional GenomicsSingle Cell SequencingMedicineSingle-cell Genomics +6

Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance

Ron C.J. Schackmann, Miranda van Amersfoort, Judith H.I. Haarhuis, +9

Journal of Clinical Investigation

Oncogenic K-Ras Turns Death Receptors Into Metastasis-Promoting Receptors in Human and Mouse Colorectal Cancer Cells

Frederik J.H. Hoogwater, Maarten W. Nijkamp, Niels Smakman, +14

Gastroenterology

Tumor BiologyOncogenic AgentMedicineApoptosisCell Death +8

A peripheral immune signature of responsiveness to PD-1 blockade in patients with classical Hodgkin lymphoma

Fathima Zumla Cader, Xihao Hu, Walter L. Goh, +15

Nature Medicine

Lymphoid NeoplasiaCancer ImmunosurveillanceAutoimmune DiseasePd-1 BlockadeImmunology +10

Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP

Duyen Amy Bui, Wendy Lee, Anne White, +5

Science Signaling

Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Ron C.J. Schackmann, Sjoerd Klarenbeek, Eva J. Vlug, +11

Cancer Research

Metastatic Breast CancerAnoikis ResistanceBreast OncologySomatic LossConditional Mouse Model +11

Nuclear p120-catenin contributes to anoikis resistance of Lobular Breast Cancer through Kaiso-dependent Wnt11 expression

Robert A. H. van de Ven, Milou Tenhagen, Wouter Meuleman, +3

Disease Models & Mechanisms