Renée R. Handley

PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia

Justin Rustenhoven, Amy M. Smith, Leon Smyth et al. · Molecular Neurodegeneration · 2018 · 165 citations · Full text

Brain urea increase is an early Huntington’s disease pathogenic event observed in a prodromal transgenic sheep model and HD cases

Renée R. Handley, Suzanne J. Reid, Rüdiger Bräuning et al. · Proceedings of the National Academy of Sciences · 2017 · 105 citations · Full text

Characterisation of PDGF-BB:PDGFRβ signalling pathways in human brain pericytes: evidence of disruption in Alzheimer’s disease

Leon Smyth, Blake Highet, Deidre Jansson et al. · Communications Biology · 2022 · 93 citations · Full text

Metabolic disruption identified in the Huntington’s disease transgenic sheep model

Renée R. Handley, Suzanne J. Reid, Stefano Patassini et al. · Scientific Reports · 2016 · 59 citations · Full text

Further Molecular Characterisation of the OVT73 Transgenic Sheep Model of Huntington's Disease Identifies Cortical Aggregates

Suzanne J. Reid, Stefano Patassini, Renée R. Handley et al. · Journal of Huntington s Disease · 2013 · 55 citations