Alexandra M. D’Ordine

TDP-43 α-helical structure tunes liquid–liquid phase separation and function

Alexander E. Conicella, Gregory L. Dignon, Gül H. Zerze et al. · Proceedings of the National Academy of Sciences · 2020 · 406 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

High-fidelity, hyper-accurate, and evolved mutants rewire atomic-level communication in CRISPR-Cas9

Erin Skeens, Souvik Sinha, Mohd Ahsan et al. · Science Advances · 2024 · 44 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Structural and dynamic insights into the HNH nuclease of divergent Cas9 species

Helen B Belato, Alexandra M. D’Ordine, Łukasz Nierzwicki et al. · Journal of Structural Biology · 2021 · 22 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

TDP-43 α-helical structure tunes liquid-liquid phase separation and function

Alexander E. Conicella, Gregory L. Dignon, Gül H. Zerze et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 21 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage

Helen B Belato, Carmelissa Norbrun, Jinping Luo et al. · The Journal of Chemical Physics · 2022 · 17 citations · Full text

Life Sciences, Biology, Molecular Biology +17