Erin Skeens

Allosteric Motions of the CRISPR–Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics

Kyle W. East, Jocelyn C. Newton, Uriel N. Morzan et al. · Journal of the American Chemical Society · 2019 · 125 citations · Full text

Principles of target DNA cleavage and the role of Mg2+ in the catalysis of CRISPR–Cas9

Łukasz Nierzwicki, Kyle W. East, Jonas M. Binz et al. · Nature Catalysis · 2022 · 76 citations

Biochemistry, Natural Sciences, Molecular Biology +6

High-fidelity, hyper-accurate, and evolved mutants rewire atomic-level communication in CRISPR-Cas9

Erin Skeens, Souvik Sinha, Mohd Ahsan et al. · Science Advances · 2024 · 36 citations · Full text

Engineering, Genetics, Cas9 Specificity +16

Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel

Georgios Pantouris, Leepakshi Khurana, Anthony Ma et al. · Cell chemical biology · 2020 · 28 citations · Full text

Mif Enzymatic Activity, Cellular Enzymology, Biochemistry +9

A topological data analytic approach for discovering biophysical signatures in protein dynamics

Wai Shing Tang, Gabriel Monteiro da Silva, Henry Kirveslahti et al. · PLoS Computational Biology · 2022 · 21 citations · Full text

Engineering, Structural Bioinformatics, Molecular Biology +19