Elisabeth Hedström

ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis

Yao Shi, Fedor Nikulenkov, Joanna Zawacka‐Pankau et al. · Cell Death and Differentiation · 2014 · 231 citations · Full text

Life Sciences, Cell Biology, Oncology +16

MDM2-Dependent Downregulation of p21 and hnRNP K Provides a Switch between Apoptosis and Growth Arrest Induced by Pharmacologically Activated p53

Martin Enge, Wenjie Bao, Elisabeth Hedström et al. · Cancer Cell · 2009 · 170 citations · Full text

Medicine, Cancer Biology, Oncology +15

p53-dependent inhibition of TrxR1 contributes to the tumor-specific induction of apoptosis by RITA

Elisabeth Hedström, Sofi Eriksson, Joanna Zawacka‐Pankau et al. · Cell Cycle · 2009 · 89 citations · Full text

Medicine, Oncology, Pharmacology +17

The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair

Sofia Henriksson, Hanif Rassoolzadeh, Elisabeth Hedström et al. · Genes & Development · 2014 · 64 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Dual Targeting of Wild-Type and Mutant p53 by Small Molecule RITA Results in the Inhibition of N-Myc and Key Survival Oncogenes and Kills Neuroblastoma Cells <i>In Vivo</i> and <i>In Vitro</i>

Mikhail Burmakin, Elisabeth Hedström, Per Kogner et al. · Clinical Cancer Research · 2013 · 61 citations

Medicine, Oncology, Pharmacology +16