Guoxun Zheng

What Contributes to Serotonin–Norepinephrine Reuptake Inhibitors’ Dual-Targeting Mechanism? The Key Role of Transmembrane Domain 6 in Human Serotonin and Norepinephrine Transporters Revealed by Molecular Dynamics Simulation

Weiwei Xue, Fengyuan Yang, Panpan Wang et al. · ACS Chemical Neuroscience · 2018 · 282 citations

Computational identification of the binding mechanism of a triple reuptake inhibitor amitifadine for the treatment of major depressive disorder

Weiwei Xue, Panpan Wang, Gao Tu et al. · Physical Chemistry Chemical Physics · 2018 · 146 citations

Drug Target, Pharmacotherapy, System Pharmacology +26

Exploring the Binding Mechanism of Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators in Clinical Trials by Molecular Dynamics Simulations

Tingting Fu, Guoxun Zheng, Gao Tu et al. · ACS Chemical Neuroscience · 2018 · 112 citations

Differentiating physicochemical properties between NDRIs and sNRIs clinically important for the treatment of ADHD

Panpan Wang, Tingting Fu, Xiaoyu Zhang et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2017 · 58 citations

Adhd, Neuropsychology, Psychiatry +8

Exploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics Study

Guoxun Zheng, Weiwei Xue, Panpan Wang et al. · Scientific Reports · 2016 · 50 citations · Full text