Concepedia
8
Publications
742
Citations
H-Index
2009
Active since
Affiliations
Amgen (United States)(Current)
Shu-Chen Lu is an author at Amgen (United States) specializing in medicine, health sciences, and cell biology.
Top concepts
MedicineHealthCell BiologyMeiosisMitosisObesityDiabetesGeneticsChromatinPathology
Publications per year
2009–2025
Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models—association with liver and adipose tissue effects
Jing Xu, Shanaka Stanislaus, Narumol Chinookoswong et al. · American Journal of Physiology-Endocrinology and Metabolism · 2009 · 331 citations
Insulin-sensitizing Action, Glucose Tolerance, Fgf21 Actions +22
A GIPR antagonist conjugated to GLP-1 analogues promotes weight loss with improved metabolic parameters in preclinical and phase 1 settings
Murielle M. Véniant, Shu-Chen Lu, Larissa Atangan et al. · Nature Metabolism · 2024 · 160 citations · Full text
GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys
Shu-Chen Lu, Michelle Chen, Larissa Atangan et al. · Cell Reports Medicine · 2021 · 80 citations · Full text
An Acyl-Ghrelin-Specific Neutralizing Antibody Inhibits the Acute Ghrelin-Mediated Orexigenic Effects in Mice
Shu-Chen Lu, Jing Xu, Narumol Chinookoswong et al. · Molecular Pharmacology · 2009 · 56 citations
Germinal Cell Aplasia in Kif18a Mutant Male Mice Due to Impaired Chromosome Congression and Dysregulated BubR1 and CENP-E
Xuesong Liu, Xudong Zhao, Yiyun Yao et al. · Genes & Cancer · 2010 · 49 citations · Full text
Spermatogenesis, Cytogenetics, Genetics +26
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