Vijay Upreti

Effect of extremes of body weight on the pharmacokinetics, pharmacodynamics, safety and tolerability of apixaban in healthy subjects

Vijay Upreti, Jessie Wang, Yu Chen Barrett et al. · British Journal of Clinical Pharmacology · 2013 · 269 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective

Tycho Heimbach, Yuan Chen, Jun Chen et al. · Clinical Pharmacology & Therapeutics · 2020 · 125 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

A Phase 1 First in Human (FIH) Study of AMG 701, an Anti-B-Cell Maturation Antigen (BCMA) Half-Life Extended (HLE) BiTE® (bispecific T-cell engager) Molecule, in Relapsed/Refractory (RR) Multiple Myeloma (MM)

Simon J. Harrison, Monique C. Minnema, Hans C. Lee et al. · Blood · 2020 · 112 citations

Life Sciences, Hematology, Immunology +17

Dose escalation results from a first-in-human, phase 1 study of glucocorticoid-induced TNF receptor–related protein agonist AMG 228 in patients with advanced solid tumors

Ben Tran, Richard D. Carvajal, Aurélien Marabelle et al. · Journal for ImmunoTherapy of Cancer · 2018 · 83 citations · Full text

Pharmacy, Oncology, Pharmacology +13

Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen

Zeynep Şafak Teksin, Insong J. Lee, Noble N. Nemieboka et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2009 · 76 citations

Pharmacy, Pharmacokinetics, Pharmacology +10