Renata Kasprzyk

2′- <i>O</i> -Methylation of the second transcribed nucleotide within the mRNA 5′ cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion

Karolina Drążkowska, Rafał Tomecki, Marcin Warmiński et al. · Nucleic Acids Research · 2022 · 82 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase

Mikołaj Żmudziński, Wioletta Rut, Kamila Olech et al. · Scientific Reports · 2023 · 43 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Synthesis of Fluorophosphate Nucleotide Analogues and Their Characterization as Tools for ¹⁹F NMR Studies

Marek R. Baranowski, Anna M. Nowicka, Anna M. Rydzik et al. · The Journal of Organic Chemistry · 2015 · 41 citations

Pharmacy, Biochemistry, Molecular Biology +13

Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase

Renata Kasprzyk, Tomasz Śpiewla, Mirosław Śmietański et al. · Antiviral Research · 2021 · 35 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect

Marcin Warmiński, Joanna Kowalska, Elżbieta Nowak et al. · ACS Chemical Biology · 2021 · 32 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15