David G. Livermore

Discovery and structure–activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor

Muna Abdi, Paul Beswick, Andy Billinton et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 70 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +10

2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: identification, stereochemistry and initial SAR

Paul G. Wyatt, Michael Allen, Alan D. Borthwick et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 66 citations

Selective Oxytocin, Medicinal Chemistry, Drug Target +10

Identification of regions of the P2X₇receptor that contribute to human and rat species differences in antagonist effects

A.D. Michel, William C. Clay, Sin‐Wei Ng et al. · British Journal of Pharmacology · 2008 · 64 citations · Full text

2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists. 2. Synthesis, Chirality, and Pharmacokinetics

Alan D. Borthwick, Dave E. Davies, Anne M. Exall et al. · Journal of Medicinal Chemistry · 2005 · 53 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Short Stereoselective Synthesis +14

2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists. 3. Synthesis, Pharmacokinetics, and in Vivo Potency

Alan D. Borthwick, Dave E. Davies, Anne M. Exall et al. · Journal of Medicinal Chemistry · 2006 · 44 citations