John V. Pluvinage

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

Julia Marschallinger, Tal Iram, Macy E. Zardeneta et al. · Nature Neuroscience · 2020 · 1.3K citations · Full text

Alzheimer's Disease, Aging, Medicine +12

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease

David Gate, Naresha Saligrama, Olivia Leventhal et al. · Nature · 2020 · 936 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Cd8 T Cells +11

Single-cell analysis reveals T cell infiltration in old neurogenic niches

Ben W. Dulken, Matthew T. Buckley, Paloma Navarro Negredo et al. · Nature · 2019 · 537 citations · Full text

Human Cell, Medicine, T-regulatory Cell +10

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains

John V. Pluvinage, Michael S. Haney, Benjamin Smith et al. · Nature · 2019 · 443 citations · Full text

Inflammation, Medicine, Immunology +3

Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes

Wendy W. Pang, John V. Pluvinage, Elizabeth Price et al. · Proceedings of the National Academy of Sciences · 2013 · 281 citations · Full text

Immunology, Immunotherapy, Aplastic Anemia +18