Matthew D. Witkin

Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms

Maria Kleppe, Richard P. Koche, Lihua Zou et al. · Cancer Cell · 2017 · 277 citations · Full text

Hematological Malignancy, Oncogenic Activation, Malignant Blood Disorder +10

ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer

Guotai Xu, Sagar Chhangawala, Emiliano Cocco et al. · Nature Genetics · 2020 · 225 citations · Full text

Radiation Oncology, Breast Oncology, Medicine +10

HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis

Yuqing Sun, Bo Zhou, Fengbiao Mao et al. · Cancer Cell · 2018 · 174 citations · Full text

Lineage Plasticity, Genetics, Medicine +2

Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation

Aaron D. Viny, Robert L. Bowman, Yu Liu et al. · Cell stem cell · 2019 · 156 citations · Full text

Chromatin, Topological Control, Chromatin Remodeling +9

Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation

Qing V. Li, Gary Dixon, Nipun Verma et al. · Nature Genetics · 2019 · 139 citations

Genome-scale Screens, Transcriptional Regulation, Induced Pluripotent Stem Cell +13