Gemma L. Dickinson

Phase I Trial of AEG35156 Administered as a 7-Day and 3-Day Continuous Intravenous Infusion in Patients With Advanced Refractory Cancer

Emma Dean, Duncan I. Jodrell, Kate Connolly et al. · Journal of Clinical Oncology · 2009 · 92 citations

Safety, tolerability, and pharmacokinetic evaluation of single‐ and multiple‐ascending doses of a novel kappa opioid receptor antagonist LY2456302 and drug interaction with ethanol in healthy subjects

Stephen L. Lowe, Conrad J. Wong, Jennifer Witcher et al. · The Journal of Clinical Pharmacology · 2014 · 90 citations

Healthy Subjects, Psychopharmacology, Pharmacotherapy +16

Identification of the Effect of Multiple Polymorphisms on the Pharmacokinetics of Simvastatin and Simvastatin Acid Using a Population-Modeling Approach

Nikolaos Tsamandouras, Gemma L. Dickinson, Yingying Guo et al. · Clinical Pharmacology & Therapeutics · 2014 · 67 citations

Development and Application of a Mechanistic Pharmacokinetic Model for Simvastatin and its Active Metabolite Simvastatin Acid Using an Integrated Population PBPK Approach

Nikolaos Tsamandouras, Gemma L. Dickinson, Yingying Guo et al. · Pharmaceutical Research · 2014 · 63 citations

Mechanistic Pharmacokinetic Model, Pharmacokinetic Modeling, Physiology +9

Evaluation of methods for achieving stable INR in healthy subjects during a multiple-dose warfarin study

Jill C. Chappell, Gemma L. Dickinson, Malcolm I. Mitchell et al. · European Journal of Clinical Pharmacology · 2011 · 62 citations

Thrombosis, Multiple-dose Warfarin Study, Healthy Subjects +9