Varnavas D. Mouchlis

Membranes serve as allosteric activators of phospholipase A ₂ , enabling it to extract, bind, and hydrolyze phospholipid substrates

Varnavas D. Mouchlis, Denis Bucher, J. Andrew McCammon et al. · Proceedings of the National Academy of Sciences · 2015 · 94 citations · Full text

Identification of putative estrogen receptor-mediated endocrine disrupting chemicals using QSAR- and structure-based virtual screening approaches

Liying Zhang, Alexander Sedykh, Ashutosh Tripathi et al. · Toxicology and Applied Pharmacology · 2013 · 81 citations · Full text

Endocrine Disruptors, Virtual Screening, Hit Identification +9

Membrane Allostery and Unique Hydrophobic Sites Promote Enzyme Substrate Specificity

Varnavas D. Mouchlis, Yuan Chen, J. Andrew McCammon et al. · Journal of the American Chemical Society · 2018 · 81 citations · Full text

Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase A2s

Daiki Hayashi, Varnavas D. Mouchlis, Edward A. Dennis · Journal of Lipid Research · 2021 · 65 citations · Full text

Molecular Modeling on Pyrimidine-Urea Inhibitors of TNF-α Production: An Integrated Approach Using a Combination of Molecular Docking, Classification Techniques, and 3D-QSAR CoMSIA

Varnavas D. Mouchlis, Georgia Melagraki, Thomas Mavromoustakos et al. · Journal of Chemical Information and Modeling · 2012 · 61 citations

Drug Target, Hit Identification, Chemical Biology +20