Concepedia

Amélie Le Bihan

AL

4

Publications

182

Citations

4

H-Index

2013

Active since

Affiliations

Swiss Tropical and Public Health Institute(Current)

Actelion (Switzerland)

Columbia University Irving Medical Center

University of Basel

Amélie Le Bihan is an author at Swiss Tropical and Public Health Institute specializing in drug discovery, molecular biology, and drug resistance.

Top concepts

Publications per year

2013–2016

4

Publications

4

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

Amélie Le Bihan, Ruben de Kanter, Íñigo Angulo‐Barturen et al. · PLoS Medicine · 2016 · 69 citations · Full text

CRISPR‐Cas9‐modified <i>pfmdr1</i> protects <i>Plasmodium falciparum</i> asexual blood stages and gametocytes against a class of piperazine‐containing compounds but potentiates artemisinin‐based combination therapy partner drugs

Caroline L. Ng, Giulia Siciliano, Mariana Justino de Almeida et al. · Molecular Microbiology · 2016 · 66 citations · Full text

Discovery and Characterization of ACT‐451840: an Antimalarial Drug with a Novel Mechanism of Action

Christoph Boss, Hamed Aissaoui, Nathalie Amaral et al. · ChemMedChem · 2016 · 26 citations

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UV-triggered Affinity Capture Identifies Interactions between the Plasmodium falciparum Multidrug Resistance Protein 1 (PfMDR1) and Antimalarial Agents in Live Parasitized Cells

Ralf Brunner, Caroline L. Ng, Hamed Aissaoui et al. · Journal of Biological Chemistry · 2013 · 21 citations · Full text

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