Maria Tardugno

Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2

Claudia Binda, Sérgio Valente, Mauro Romanenghi et al. · Journal of the American Chemical Society · 2010 · 283 citations

Drug Target, Chromatin State, Lsd2 Histone Demethylases +16

Study of 1,4-Dihydropyridine Structural Scaffold: Discovery of Novel Sirtuin Activators and Inhibitors

Antonello Mai, Sérgio Valente, Sarah Meade et al. · Journal of Medicinal Chemistry · 2009 · 159 citations · Full text

Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells

Sérgio Valente, Yiwei Liu, Michaël Schnekenburger et al. · Journal of Medicinal Chemistry · 2014 · 129 citations · Full text

Epigenetic Change, Dna Methylation, Cancer Biology +19

Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension

Mark G. Lewis, Sandrina DaFonseca, Nicolas Chomont et al. · AIDS · 2011 · 92 citations

1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells

Sérgio Valente, Paolo Mellini, Francesco Spallotta et al. · Journal of Medicinal Chemistry · 2015 · 78 citations

Chemoprevention Strategy, Molecular Biology, Cancer Biology +18