Saúl C. Costa

Multimodal molecular encapsulation of nicardipine hydrochloride by β-cyclodextrin, hydroxypropyl-β-cyclodextrin and triacetyl-β-cyclodextrin in solution. Structural studies by 1H NMR and ROESY experiments

Catarina Marques Fernandes, Rui A. Carvalho, Saúl C. Costa et al. · European Journal of Pharmaceutical Sciences · 2003 · 118 citations

Medicinal Chemistry, Supramolecular Assembly, Engineering +11

Development, optimization and application of an analytical methodology by ultra performance liquid chromatography–tandem mass spectrometry for determination of amanitins in urine and liver samples

Marta Leite, Andreia Freitas, Anabela Marisa Azul et al. · Analytica Chimica Acta · 2013 · 41 citations

Medicine, Bioanalysis, Mass Spectrometry +11

Exemestane metabolites: Synthesis, stereochemical elucidation, biochemical activity and anti-proliferative effects in a hormone-dependent breast cancer cell line

Carla Varela, Cristina Amaral, E. J. Tavares da Silva et al. · European Journal of Medicinal Chemistry · 2014 · 39 citations · Full text

Biochemistry, Stereochemical Elucidation, Medicine +9

Anti-tumor efficacy of new 7α-substituted androstanes as aromatase inhibitors in hormone-sensitive and resistant breast cancer cells

Cristina Amaral, Carla Varela, João Maurício et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2017 · 33 citations

Aromatase Inhibitors, Breast Oncology, Endocrine-related Cancer +11

C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure–Activity Relationships

Fernanda M.F. Roleira, Carla Varela, Cristina Amaral et al. · Journal of Medicinal Chemistry · 2019 · 31 citations · Full text