Carla Varela - Concepedia

Author

Carla Varela

Also Known As

C. L. Varela, C. Varela, C. Varela-Lopes, Carla L. Varela, Carla L. Varela, Carla Varela, Christina G. Varela, Correia, Fernando, Estevez Varela, Carla, Pontificia Universidad Católica de Chile

Publications

1.6K

Citations

H-Index

Concepts

All Affiliations

University of Coimbra Universidade do Porto Rede de Química e Tecnologia Magna Graecia University Universidade de Santiago de Compostela

About

Carla Varela is an author at University of Coimbra specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	15	16	558
2	Biochemistry	7	7	317
3	Natural Sciences	5	5	213
4	Engineering	2	2	44
5	Biomedical Engineering	1	1	27

Carla Varela

Publications

670

Citations

H-Index

Page 1

	Year	Citations
New Structure–Activity Relationships of A- and D-Ring Modified Steroidal Aromatase Inhibitors: Design, Synthesis, and Biochemical Evaluation Carla Varela, E. J. Tavares da Silva, Cristina Amaral, Journal of Medicinal Chemistry Bioorganic ChemistryOrganic ChemistryDiversity Oriented SynthesisStereoselective SynthesisSteroid Metabolism	2012	67
New insights into highly potent tyrosinase inhibitors based on 3-heteroarylcoumarins: Anti-melanogenesis and antioxidant activities, and computational molecular modeling studies Francesca Pintus, María João Matos, Santiago Vilar, Bioorganic & Medicinal Chemistry BiochemistryMedicineRational Drug DesignPotent Tyrosinase InhibitorsAntioxidant Activities	2017	65
Design and discovery of tyrosinase inhibitors based on a coumarin scaffold María João Matos, Carla Varela, Santiago Vilar, RSC Advances Combinatorial ChemistryMolecular PharmacologyMedicinal ChemistryTyrosinase Inhibitory ActivityPharmaceutical Science	2015	56
New phenolic cinnamic acid derivatives as selective COX-2 inhibitors. Design, synthesis, biological activity and structure-activity relationships Daniela Ribeiro, Carina Proença, Carla Varela, Bioorganic Chemistry Biological ActivityMedicinal ChemistryBiochemistryNatural SciencesMedicine	2019	47
Effects of steroidal aromatase inhibitors on sensitive and resistant breast cancer cells: Aromatase inhibition and autophagy Cristina Amaral, Carla Varela, Margarida Azevedo, The Journal of Steroid Biochemistry and Molecular Biology Breast OncologyAromatase InhibitionMedicineAromataseBreast Cancer	2013	41
Exemestane metabolites: Synthesis, stereochemical elucidation, biochemical activity and anti-proliferative effects in a hormone-dependent breast cancer cell line Carla Varela, Cristina Amaral, E. J. Tavares da Silva, European Journal of Medicinal Chemistry BiochemistryStereochemical ElucidationMedicineBreast CancerExemestane Metabolites	2014	39
Anti-tumor efficacy of new 7α-substituted androstanes as aromatase inhibitors in hormone-sensitive and resistant breast cancer cells Cristina Amaral, Carla Varela, João Maurício, The Journal of Steroid Biochemistry and Molecular Biology Aromatase InhibitorsBreast OncologyEndocrine-related CancerMedicineBreast Cancer	2017	33
Steroidal aromatase inhibitors inhibit growth of hormone-dependent breast cancer cells by inducing cell cycle arrest and apoptosis Cristina Amaral, Carla Varela, Margarida Borges, APOPTOSIS Breast OncologyMedicineCell Cycle ArrestAromataseBreast Cancer	2013	32
C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure–Activity Relationships Fernanda M.F. Roleira, Carla Varela, Cristina Amaral, Journal of Medicinal Chemistry	2019	31
miR-145-loaded micelleplexes as a novel therapeutic strategy to inhibit proliferation and migration of osteosarcoma cells Mariana Magalhães, Mauro Sousa de Almeida, E. J. Tavares da Silva, European Journal of Pharmaceutical Sciences Tumor BiologyMir-145-loaded MicelleplexesOsteosarcoma CellsMicrorna DetectionTumor Targeting	2018	29

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