Carla Varela

New Structure–Activity Relationships of A- and D-Ring Modified Steroidal Aromatase Inhibitors: Design, Synthesis, and Biochemical Evaluation

Carla Varela, E. J. Tavares da Silva, Cristina Amaral et al. · Journal of Medicinal Chemistry · 2012 · 67 citations · Full text

Bioorganic Chemistry, Organic Chemistry, Diversity Oriented Synthesis +17

New insights into highly potent tyrosinase inhibitors based on 3-heteroarylcoumarins: Anti-melanogenesis and antioxidant activities, and computational molecular modeling studies

Francesca Pintus, María João Matos, Santiago Vilar et al. · Bioorganic & Medicinal Chemistry · 2017 · 65 citations · Full text

Biochemistry, Medicine, Rational Drug Design +7

Design and discovery of tyrosinase inhibitors based on a coumarin scaffold

María João Matos, Carla Varela, Santiago Vilar et al. · RSC Advances · 2015 · 56 citations

Combinatorial Chemistry, Molecular Pharmacology, Medicinal Chemistry +13

New phenolic cinnamic acid derivatives as selective COX-2 inhibitors. Design, synthesis, biological activity and structure-activity relationships

Daniela Ribeiro, Carina Proença, Carla Varela et al. · Bioorganic Chemistry · 2019 · 47 citations · Full text

Biological Activity, Medicinal Chemistry, Biochemistry +9

Effects of steroidal aromatase inhibitors on sensitive and resistant breast cancer cells: Aromatase inhibition and autophagy

Cristina Amaral, Carla Varela, Margarida Azevedo et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 41 citations

Breast Oncology, Aromatase Inhibition, Medicine +9