Stefan Pöhlmann

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Markus Hoffmann, Hannah Kleine‐Weber, Simon Schroeder et al. · Cell · 2020 · 21.1K citations · Full text

Medicine, Viral Pathogenesis, Immunology +8

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells

Markus Hoffmann, Hannah Kleine‐Weber, Stefan Pöhlmann · Molecular Cell · 2020 · 2.1K citations · Full text

Virus Structure, Multibasic Cleavage Site, Viral Evolution +9

Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response

Ilona Glowacka, Stephanie Bertram, Marcel A. Müller et al. · Journal of Virology · 2011 · 1.2K citations · Full text

Membrane Fusion, Protease Inhibitors, Humoral Immune Response +15

SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies

Markus Hoffmann, Prerna Arora, Rüdiger Groß et al. · Cell · 2021 · 1K citations · Full text

Immunology, Virology, Viral Structural Protein +3

The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic

Markus Hoffmann, Nadine Krüger, Sebastian Schulz et al. · Cell · 2021 · 945 citations · Full text

Covid-19 Pandemic, Immunology, Antibody-mediated Neutralization +9