Caryn Lawrence

Optimisation and validation of a medium-throughput electrophysiology-based hNav1.5 assay using IonWorks™

Alexander R. Harmer, Najah Abi‐Gerges, Alison Easter et al. · Journal of Pharmacological and Toxicological Methods · 2007 · 120 citations

Engineering, Bioengineering, Pharmacology +10

Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells

M. F. Kendellen, Jennifer W. Bradford, Caryn Lawrence et al. · Oncogene · 2013 · 118 citations

Medicine, Cancer Biology, Oncology +14

A Rabbit Langendorff Heart Proarrhythmia Model: Predictive Value for Clinical Identification of Torsades de Pointes

Caryn Lawrence, M H Bridgland‐Taylor, C.E. Pollard et al. · British Journal of Pharmacology · 2006 · 85 citations · Full text

Medicine, Cardiology, Pharmacology +16

Gliclazide produces high-affinity block of K ATP channels in mouse isolated pancreatic beta cells but not rat heart or arterial smooth muscle cells

Caryn Lawrence, Peter Proks, Glenn C. Rodrigo et al. · Diabetologia · 2001 · 74 citations · Full text

Medicine, Pharmacology, Physiology +15

The K_ATP channel opener diazoxide protects cardiac myocytes during metabolic inhibition without causing mitochondrial depolarization or flavoprotein oxidation

Caryn Lawrence, Brian Billups, Glenn C. Rodrigo et al. · British Journal of Pharmacology · 2001 · 74 citations · Full text

Life Sciences, Pharmacology, Physiology +17