M. Edward Medof

Locally Produced Complement Fragments C5a and C3a Provide Both Costimulatory and Survival Signals to Naive CD4+ T Cells

Michael G. Strainic, Jinbo Liu, Danping Huang et al. · Immunity · 2008 · 565 citations · Full text

Complement System, Survival Signals, Autoimmune Disease +10

Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes.

M. Edward Medof, Taroh Kinoshita, Victor Nussenzweig · The Journal of Experimental Medicine · 1984 · 560 citations · Full text

Immunocytochemical Technique, Immunology, Blood Cell +21

Identification of the complement decay-accelerating factor (DAF) on epithelium and glandular cells and in body fluids.

M. Edward Medof, E I Walter, Joanne L. Rutgers et al. · The Journal of Experimental Medicine · 1987 · 339 citations · Full text

Immunocytochemical Technique, Laboratory Immunology, Immunology +25

Unique role of the complement receptor CR1 in the degradation of C3b associated with immune complexes.

M. Edward Medof, Kei Iida, Carolyn Mold et al. · The Journal of Experimental Medicine · 1982 · 332 citations · Full text

Complement Receptor Cr1, Innate Immune System, Immunology +18

Absence of signaling into CD4+ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3+ regulatory T cells

Michael G. Strainic, Ethan M. Shevach, Fengqi An et al. · Nature Immunology · 2012 · 293 citations · Full text

Autoinductive Tgf-β1 Signaling, Signal Transduction, Cd4+ Cells +13