Impact of RNA degradation on gene expression profiling

Lennart Opitz, Gabriela Salinas-Riester, Marian Grade, +6

BMC Medical Genomics

Mutated <i>KRAS</i> results in overexpression of <i>DUSP4</i>, a MAP‐kinase phosphatase, and <i>SMYD3</i>, a histone methyltransferase, in rectal carcinomas

Jochen Gaedcke, Marian Grade, Klaus Jung, +10

Genes Chromosomes and Cancer

PathologyCancer BiologyEpigeneticsTumor BiologyCancer Cell Biology +21

Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling

Georg Emons, Melanie Spitzner, Sebastian Reineke, +13

Molecular Cancer Research

STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy <i>in vitro</i> and <i>in vivo</i>

Melanie Spitzner, Birte Roesler, Christian Bielfeld, +12

International Journal of Cancer

ImmunologyCancer BiologyTumor BiologyOncologyGastrointestinal Oncology +15

Colorectal cancer susceptibility loci as predictive markers of rectal cancer prognosis after surgery

Yue Hu, Jochen Gaedcke, Georg Emons, +9

Genes Chromosomes and Cancer

Surgical OncologyColorectal SurgeryGeneticsGastroenterologyPathology +15

Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy

Emil Kendziorra, Kerstin Ahlborn, Melanie Spitzner, +12

Carcinogenesis

Tumor BiologyTranscriptional RegulationRadiation MedicineOncologyGastrointestinal Oncology +11

Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer

Jordi Camps, Jason J. Pitt, Georg Emons, +10

Cancer Research

A Gene Expression Signature for Chemoradiosensitivity of Colorectal Cancer Cells

Melanie Spitzner, Georg Emons, Frank Krämer, +9

International Journal of Radiation Oncology*Biology*Physics

Gene Expression SignatureRadiation OncologyMedicineColorectal CancerCancer Genomics +7

Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells

Amanda B. Hummon, Jason J. Pitt, Jordi Camps, +10

Molecular Cancer

A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets

Marian Grade, Amanda B. Hummon, Jordi Camps, +11

International Journal of Cancer