Laura Lowe Furge

Cytochrome P450 enzymes in drug metabolism and chemical toxicology: An introduction

Laura Lowe Furge, F. Peter Guengerich · Biochemistry and Molecular Biology Education · 2006 · 180 citations

Medicine, Biochemistry, Toxicology +14

Inhibition of Human Cytochrome P450 Enzymes by 1,2-Dithiole-3-thione, Oltipraz and Its Derivatives, and Sulforaphane

Sophie Langouët, Laura Lowe Furge, Nathalie Kerriguy et al. · Chemical Research in Toxicology · 2000 · 116 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Analysis of Nucleotide Insertion and Extension at 8-Oxo-7,8-dihydroguanine by Replicative T7 Polymerase exo^- and Human Immunodeficiency Virus-1 Reverse Transcriptase Using Steady-State and Pre-Steady-State Kinetics

Laura Lowe Furge, F. Peter Guengerich · Biochemistry · 1997 · 105 citations

Life Sciences, Biochemistry, Molecular Biology +13

Metoclopramide is metabolized by CYP2D6 and is a reversible inhibitor, but not inactivator, of CYP2D6

Mara R. Livezey, Erran D. Briggs, Amanda K. Bolles et al. · Xenobiotica · 2013 · 48 citations

Medicine, Pharmacokinetics, Pharmacology +13

Explanation of Pre-Steady-State Kinetics and Decreased Burst Amplitude of HIV-1 Reverse Transcriptase at Sites of Modified DNA Bases with an Additional, Nonproductive Enzyme−DNA−Nucleotide Complex

Laura Lowe Furge, F. Peter Guengerich · Biochemistry · 1999 · 40 citations

Life Sciences, Biochemistry, Molecular Biology +17