Hans‐Dieter Gerber

Virtual Screening for Submicromolar Leads of tRNA-guanine Transglycosylase Based on a New Unexpected Binding Mode Detected by Crystal Structure Analysis

Ruth Brenk, Ulrich Grädler, Hans‐Dieter Gerber et al. · Journal of Medicinal Chemistry · 2003 · 103 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +16

A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase11Edited by R. Huber

Ulrich Grädler, Hans‐Dieter Gerber, DeeAnne M Goodenough-Lashua et al. · Journal of Molecular Biology · 2001 · 76 citations

Pharmacy, Biochemistry, Molecular Biology +7

Kinetic and Structural Insights into the Mechanism of Binding of Sulfonamides to Human Carbonic Anhydrase by Computational and Experimental Studies

Roberto Gaspari, C. Rechlin, A. Heine et al. · Journal of Medicinal Chemistry · 2015 · 67 citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Paradoxically, Most Flexible Ligand Binds Most Entropy-Favored: Intriguing Impact of Ligand Flexibility and Solvation on Drug–Kinase Binding

B. Wienen-Schmidt, Hendrik R. A. Jonker, Tobias Wulsdorf et al. · Journal of Medicinal Chemistry · 2018 · 49 citations · Full text

Natural Sciences, Biophysics, Chemistry +17

Structural insights into the stimulation of S. pombe Dnmt2 catalytic efficiency by the tRNA nucleoside queuosine

Sven Johannsson, Piotr Neumann, Alexander Wulf et al. · Scientific Reports · 2018 · 37 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13