Hideki Ushirogochi

5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of β-lactamases

Aranapakam M. Venkatesan, Atul Agarwal, Takao Abé et al. · Bioorganic & Medicinal Chemistry · 2007 · 66 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

In Vitro and In Vivo Activities of Novel 6-Methylidene Penems as β-Lactamase Inhibitors

Jason Weiss, Peter J. Petersen, Timothy M. Murphy et al. · Antimicrobial Agents and Chemotherapy · 2004 · 54 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Novel imidazole substituted 6-methylidene-penems as broad-spectrum β-lactamase inhibitors

Aranapakam M. Venkatesan, Atul Agarwal, Takao Abé et al. · Bioorganic & Medicinal Chemistry · 2004 · 45 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Structure-Activity Relationship of 6-Methylidene Penems Bearing 6,5 Bicyclic Heterocycles as Broad-Spectrum β-Lactamase Inhibitors:  Evidence for 1,4-Thiazepine Intermediates with C7 R Stereochemistry by Computational Methods

Aranapakam M. Venkatesan, Atul Agarwal, Takao Abé et al. · Journal of Medicinal Chemistry · 2006 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Mechanism of Inactivation of β-Lactamases by Novel 6-Methylidene Penems Elucidated Using Electrospray Ionization Mass Spectrometry

Keiko Tabei, Xidong Feng, Aranapakam M. Venkatesan et al. · Journal of Medicinal Chemistry · 2004 · 27 citations · Full text

Natural Sciences, Biochemistry, Chemistry +14