Darwin Ye

Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade

Joseph L. Benci, Lexus R. Johnson, Ruth Choa et al. · Cell · 2019 · 521 citations · Full text

Immune Evasion, Cancer Immunosurveillance, Interferon Coordinate Adaptive +12

The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance autonomous and endogenous immune function

Lexus R. Johnson, Daniel Y. Lee, Jacqueline S. Eacret et al. · Cell · 2021 · 177 citations · Full text

Inflammation, Immunological Memory, Autoimmune Disease +12

Combined JAK inhibition and PD-1 immunotherapy for non–small cell lung cancer patients

Divij Mathew, Melina E. Marmarelis, Caitlin Foley et al. · Science · 2024 · 160 citations · Full text

Persistent Inflammation Refractory, Immunology, Immunologic Mechanism +19

Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer

Danish Memon, Adam J. Schoenfeld, Darwin Ye et al. · Cancer Cell · 2024 · 146 citations · Full text

Immunology, Immunoediting, Immunotherapeutics +19

Cancer cells resistant to immune checkpoint blockade acquire interferon-associated epigenetic memory to sustain T cell dysfunction

Jingya Qiu, Bihui Xu, Darwin Ye et al. · Nature Cancer · 2023 · 95 citations

Immunological Memory, Cancer Immunosurveillance, T Cell Dysfunction +11