Elena Gustchina

Increased fitness of drug resistant HIV-1 protease as a result of acquisition of compensatory mutations during suboptimal therapy

Monique Nijhuis, Rob Schuurman, Dorien de Jong et al. · AIDS · 1999 · 378 citations

Life Sciences, Infectious Diseases, Microbiology +17

Mirabamides A–D, Depsipeptides from the Sponge <i>Siliquariaspongia mirabilis</i> That Inhibit HIV-1 Fusion

Alberto Plaza, Elena Gustchina, Heather L. Baker et al. · Journal of Natural Products · 2007 · 148 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Solution Structure of the Monovalent Lectin Microvirin in Complex with Manα(1–2)Man Provides a Basis for Anti-HIV Activity with Low Toxicity

Syed Shahzad‐ul‐Hussan, Elena Gustchina, Rodolfo Ghirlando et al. · Journal of Biological Chemistry · 2011 · 73 citations · Full text

Life Sciences, Biochemistry, Biology +17

Drug resistance mutations can affect dimer stability of HIV‐1 protease at neutral pH

Dong Xie, Sergei Gulnik, Elena Gustchina et al. · Protein Science · 1999 · 73 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Dissection of the pH Dependence of Inhibitor Binding Energetics for an Aspartic Protease:  Direct Measurement of the Protonation States of the Catalytic Aspartic Acid Residues^,

Dong Xie, Sergei Gulnik, L.N. Collins et al. · Biochemistry · 1997 · 64 citations

Life Sciences, Biochemistry, Biophysics +17