S.‐C. TSAY

Designed Enediynes: A New Class of DNA-Cleaving Molecules with Potent and Selective Anticancer Activity

K. C. Nicolaou, Wei‐Min Dai, S.‐C. TSAY et al. · Science · 1992 · 325 citations

Combinatorial Chemistry, Dna Nanotechnology, Medicinal Chemistry +15

Molecular design, chemical synthesis, kinetic studies, calculations, and biological studies of novel enediynes equipped with triggering, detection, and deactivating devices. Model dynemicin A epoxide and cis-diol systems

K. C. Nicolaou, Wei‐Min Dai, Y. P. Hong et al. · Journal of the American Chemical Society · 1993 · 84 citations

Novel enediynes equipped with triggering and detection devices. Isolation of cis-diol models of the dynemicin a cascade

K. C. Nicolaou, Y. P. Hong, Yu‐suke Torisawa et al. · Journal of the American Chemical Society · 1991 · 40 citations

Cis-diol Models, Bioorganic Chemistry, Engineering +18

On the mechanism of activation of designed enediynes with selective cytotoxicity

K. C. Nicolaou, Wei‐Min Dai, S.‐C. TSAY et al. · Bioorganic & Medicinal Chemistry Letters · 1992 · 16 citations

Medicinal Chemistry, Mechanism Of Action, Selective Cytotoxicity +4