Heidi H. Pak

The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine

Deyang Yu, Nicole E. Richardson, Cara L. Green et al. · Cell Metabolism · 2021 · 358 citations · Full text

Energy Metabolism, Biochemistry, Adverse Metabolic Effects +6

Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and life span in mice

Nicole E. Richardson, Elizabeth N. Konon, Haley S. Schuster et al. · Nature Aging · 2021 · 250 citations · Full text

Caloric Restriction, Lifespan Extension, Life Span +10

Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice

Heidi H. Pak, Spencer A. Haws, Cara L. Green et al. · Nature Metabolism · 2021 · 174 citations · Full text

Obesity, Metabolic Syndrome, Nutrition +11

Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction

Cara L. Green, Heidi H. Pak, Nicole E. Richardson et al. · Cell Metabolism · 2022 · 105 citations · Full text

Metabolic Syndrome, Energy Metabolism, Metabolic Disorder +13

Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice

Cara L. Green, Michaela E. Trautman, Krittisak Chaiyakul et al. · Cell Metabolism · 2023 · 94 citations · Full text

Caloric Restriction, Nutrition, Heterogeneous Mice +8