Sai Kiran Naineni

Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A

Sai Kiran Naineni, Jason Liang, Kenneth G. Hull et al. · Cell chemical biology · 2021 · 42 citations · Full text

Crystal Structure, Functional Mimicry, Biochemistry +8

A comparative study of small molecules targeting eIF4A

Sai Kiran Naineni, Rayelle Itoua Maïga, Regina Cencic et al. · RNA · 2020 · 39 citations · Full text

Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5′ leader regions

Jutta Steinberger, Leo Shen, Stephen J. Kiniry et al. · Nucleic Acids Research · 2020 · 39 citations · Full text

Molecular Regulation, Molecular Biology, Eif4a-dependent Mrnas +19

A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer

Regina Cencic, Young Kyuen Im, Sai Kiran Naineni et al. · Proceedings of the National Academy of Sciences · 2024 · 18 citations · Full text

Breast Oncology, Engineering, Mrna Translation +19

Exploring the targeting spectrum of rocaglates among eIF4A homologs

Sai Kiran Naineni, Regina Cencic, Françis Robert et al. · RNA · 2023 · 10 citations · Full text