Daniel Eikel

Teratogenic Effects Mediated by Inhibition of Histone Deacetylases:  Evidence from Quantitative Structure Activity Relationships of 20 Valproic Acid Derivatives

Daniel Eikel, Alfonso Lampen, Heinz Nau · Chemical Research in Toxicology · 2006 · 122 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Valproic acid induces extracellular signal-regulated kinase 1/2 activation and inhibits apoptosis in endothelial cells

Martin Michaelis, Tatyana Suhan, Uwe Michaelis et al. · Cell Death and Differentiation · 2005 · 91 citations

Life Sciences, Cell Biology, Pharmacology +14

Effects of Valproic Acid Derivatives on Inositol Trisphosphate Depletion, Teratogenicity, Glycogen Synthase Kinase-3β Inhibition, and Viral Replication: A Screening Approach for New Bipolar Disorder Drugs Derived from the Valproic Acid Core Structure

Britta J. Eickholt, Greg J. Towers, W.J. Ryves et al. · Molecular Pharmacology · 2005 · 70 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Increased Replication of Human Cytomegalovirus in Retinal Pigment Epithelial Cells by Valproic Acid Depends on Histone Deacetylase Inhibition

Martin Michaelis, Tatyana Suhan, Alexander Reinisch et al. · Investigative Ophthalmology & Visual Science · 2005 · 36 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Increased human cytomegalovirus replication in fibroblasts after treatment with therapeutical plasma concentrations of valproic acid

Martin Michaelis, N.Gail Kohler, Alexander Reinisch et al. · Biochemical Pharmacology · 2004 · 29 citations

Life Sciences, Biomedical Sciences, Infectious Diseases +13