Karin V. Niessen

Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro

Thomas Seeger, Martin Eichhorn, Michael Lindner et al. · Toxicology · 2012 · 58 citations

Rat Muscle, Soman-blocked Neuromuscular Transmission, Muscle Function +12

Interaction of bispyridinium compounds with the orthosteric binding site of human α7 and Torpedo californica nicotinic acetylcholine receptors (nAChRs)

Karin V. Niessen, John E.H. Tattersall, Christopher M. Timperley et al. · Toxicology Letters · 2011 · 37 citations

Molecular Pharmacology, Biochemistry, Medicine +6

Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor

Sonja Sichler, Georg Höfner, S. Rappenglück et al. · Toxicology Letters · 2017 · 27 citations

Signal Transduction, Biochemistry, Functional Selectivity +13

Affinities of bispyridinium non-oxime compounds to [3H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length

Karin V. Niessen, Thomas Seeger, John E.H. Tattersall et al. · Chemico-Biological Interactions · 2013 · 26 citations

Bispyridinium Non-oxime Compounds, Biochemistry, Functional Selectivity +8

In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers

Karin V. Niessen, Thomas Seeger, S. Rappenglück et al. · Toxicology Letters · 2017 · 25 citations

Molecular Pharmacology, Biochemistry, Medicine +6