Xuwei Shao

Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity

Uday Kiran Velagapudi, Marie-France Langelier, Cristina Delgado-Martín et al. · Journal of Medicinal Chemistry · 2019 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Chemical Space Exploration around Thieno[3,2-<i>d</i>]pyrimidin-4(3<i>H</i>)-one Scaffold Led to a Novel Class of Highly Active <i>Clostridium difficile</i> Inhibitors

Xuwei Shao, Ahmed AbdelKhalek, Nader S. Abutaleb et al. · Journal of Medicinal Chemistry · 2019 · 36 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis of 2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide and 3-oxo-3,4-dihydrobenzo[b][1,4]oxazine-8-carboxamide derivatives as PARP1 inhibitors

Xuwei Shao, Steven Pak, Uday Kiran Velagapudi et al. · Bioorganic Chemistry · 2020 · 12 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +7