John Harrelson

Prediction of CYP3A-Mediated Drug-Drug Interactions Using Human Hepatocytes Suspended in Human Plasma

Jialin Mao, Michael A. Mohutsky, John Harrelson et al. · Drug Metabolism and Disposition · 2011 · 56 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

UGT2B17 Genetic Polymorphisms Dramatically Affect the Pharmacokinetics of MK-7246 in Healthy Subjects in a First-in-Human Study

Michele Trucksis, Joshua McElwee, P H Wong et al. · Clinical Pharmacology & Therapeutics · 2012 · 46 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +13

Predictions of Cytochrome P450-Mediated Drug-Drug Interactions Using Cryopreserved Human Hepatocytes: Comparison of Plasma and Protein-Free Media Incubation Conditions

Jialin Mao, Michael A. Mohutsky, John Harrelson et al. · Drug Metabolism and Disposition · 2012 · 42 citations

Medicine, Pharmacokinetics, Pharmacology +17

Multiple-Ligand Binding in CYP2A6: Probing Mechanisms of Cytochrome P450 Cooperativity by Assessing Substrate Dynamics

John Harrelson, William M. Atkins, Sidney D. Nelson · Biochemistry · 2008 · 40 citations

Pharmacy, Biochemistry, Pharmacology +17

Inactivation of CYP2A6 by the Dietary Phenylpropanoid trans-Cinnamic Aldehyde (Cinnamaldehyde) and Estimation of Interactions with Nicotine and Letrozole

Stephen M. Black, Aleksandar Todorović, Fawzy Elbarbry et al. · Drug Metabolism and Disposition · 2016 · 22 citations · Full text

Medicine, Biochemistry, Pharmacology +17